Multifunctional Nanocarriers provides information on the concept, theory and application of multifunctional nanocarriers. The book covers current research, beginning with product strategy, targeted drug delivery, and advanced drug delivery approaches, along with numerous multifunctional nanocarriers and their regulatory considerations for product development. The book covers targeting, receptor mediated targeting, and recent advancements using multifunctional nanocarriers and their regulatory aspects. This is an important reference source for materials scientists and engineers who want to learn more about how multifunctional nanocarriers are applied in a range of biomedical applications.
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Table of Contents
Section A: Targeted Drug Delivery and Targeting 1. Nanotechnology: Advanced Drug Targeting Concepts, Fundamentals, and Strategies 2. Advanced Multifunctional Nanomaterials An Introduction 3. Receptors Based Drug Targeting and Targeted Drug Delivery 4. Quality by Design (QbD) Approach in Drug Delivery Systems and Drug Targeting 5. Mitochondrial Targeting Strategies and Applications 6. Mucosal Vaccine Delivery and Targeting and Drug Delivery Strategies 7. Ophthalmic Drug Delivery; Opportunities, Major Challenges, and Application 8. Nano-immuno-adjuvants-based Immunotherapy in the Treatment of Cancer 9. Brain Targeting Drug Delivery Systems for the Management of Brain Disorders: Molecular targets and nano-technological strategies 10. Drug Delivery Through Nails: Concept, Theory and Application
Section B: Multifunctional Nano-carriers in Drug Delivery and Targeting 11. Dendrimers-specific Drug Delivery and Drug Targeting 12. Nanoparticles-mediated Drug Targeting Strategies 13. Carbon Nanotubes in Controlled and Targeted Drug Delivery 14. Liposomal Formulation: Current Landscape and Industrial Applicability 15. Self-emulsifying Drug Delivery and Targeting 16. Pro-drug Strategy in Drug Targeting & Delivery 17. Graphenes and Fullerenes as Drug Delivery Systems 18. Quantum Dots (QDs) in Biomedical Applications 19. Drug-conjugate Strategies in Drug Delivery 20. Colloidosomes in Drug Delivery and Targeting 21. Polymeric Micelles, Role, Implication in Drug Delivery 22. Nano emulsion-based Delivery and Targeting 23. Solid Lipid Nanoparticles as Drug Carriers 24. Cochleates as Nanoparticles Drug Carriers in Drug Delivery 25. Super-paramagnetic Iron Oxide Nanoparticles (SPION) in Drug Delivery 26. Role of Pharmacokinetics/Pharmacodynamics Modeling in Drug Targeting 27. Nano-toxicology: Toxicity and Safety Issue of Nanomaterials 28. Exosomes-mediated Drug Delivery 29. Current Status of FDA Approved Market Products
Authors
Neelesh Kumar Mehra Senior Research Scientist, Sentiss Research Center, Haryana, India. Neelesh Kumar Mehra is Senior Research Scientist at the Sentiss Research Center, Haryana, India. His area of research is in the design, development, evaluation of ophthalmic nanoemulsion, lipospheres, liposomes, fullerenes, and nanoparticles for topical/parenteral delivery of drugs/biomolecules. Saurabh Srivastava Associate Professor of Pharmeceutics, National Institute of Pharmaceutical Education and Research, Hyderabad, India. Saurabh Srivastava is an Associate Professor of Pharmaceutics, at the National Institute of Pharmaceutical Education and Research, Hyderabad, India. His research interests include the development and optimization of industrially viable, feasible and scalable differentiated formulations, for the purpose of bioavailability enhancement, food effect minimization, repurposing/new indication, synergism for FDCs, and dose/dosing frequency reduction. Jitender Madan Associate Professor, National Institute of Pharmaceutical Education and Research, Hyderabad, Telangana, India. Dr. Madan's major areas of research include Self-assembled Supramolecular systems viz. liposomes, niosomes, cyclodextrin, nano- & micro-particles and solid-lipid nanoparticles. The focus is centered onto the exploitation of US FDA approved biomaterials in combination with other potential lipids and polymers to develop the innovative dosage forms and drug delivery systems in order to improve the bioavailability, stability, safety (tolerance) and patient-compliance.Whilst a wide range of applications are being taken up, the special emphasis is given to augment the aqueous solubility and bioavailability of lipophilic drugs. Pankaj Kumar Singh Department of Pharmaceutics, National Institute of Pharmaceutical Education and Research (NIPER), Hyderabad, Telangana 500037, India.
Dr. Pankaj Kumar Singh, Ph.D., is currently working as an Assistant Professor in the Department of Pharmaceutics at the National Institute of Pharmaceutical Education and Research-Hyderabad (NIPER-Hyderabad) India. He has received his Doctorate in Pharmaceutics from CSIR-Central Drug Research Institute, Lucknow, India. He has been closely associated with several scientific and socially impactful projects funded by various prestigious bodies like TSCOST-DBT, CCRUM, DST, ICMR and Department of Pharmaceuticals, Ministry of Chemicals and Fertilizers, Government of India.
He has gained experience of over a decade in the field of teaching and research related to pharmaceuticals. He has more than 10 years of experience in working on targeted drug delivery systems for various hydrophobic and hydrophilic drug candidates. He has gained experience in the development of peptide-based liposomal delivery and ligand anchored delivery systems for the treatment of various life-threatening diseases, especially cancer and visceral leishmaniasis. He has published more than 85 quality papers along with reviews in journals of high repute and has a cumulative impact factor of more than 500, h-index 24, i10 index 44 and 1675 citations. He has edited 5 books, co-authored 40 book chapters and filed 7 patents with 2 patents granted. He is also involved in technology transfer of one product.
He has also bagged several accolades like the "CSIR-Research Associate� award, "CSIR-Senior Research Fellowship� award, two times travel grant award and financial Assistance and Incentive award for research paper publication. He has been keenly involved and associated with allied works say posters, abstracts, symposiums, invited talks, training and workshop and other research activities. He holds the membership of several nationally and internationally recognized bodies of repute like the Indian Pharma Education Society, Indian Science Congress Association and Bioencapsulation Research Group. He is a peer reviewer of various international Journals and publishers. He has guided 26 M.S. students for their dissertations/research projects and 11 Ph.D. students continuing their research work under his guidance. He has rich research and teaching experience in the formulation and development of various novel and targeted drug delivery systems.
