The duchenne muscular dystrophy market size has grown strongly in recent years. It will grow from $1.07 billion in 2023 to $1.17 billion in 2024 at a compound annual growth rate (CAGR) of 9.2%. The growth observed in the historical period can be attributed to advancements in genetic understanding and diagnostics, progress in clinical trials, increased patient advocacy and awareness, orphan drug designation and incentives, and collaborative research initiatives.
The duchenne muscular dystrophy market size is expected to see strong growth in the next few years. It will grow to $1.61 billion in 2028 at a compound annual growth rate (CAGR) of 8.2%. The anticipated growth in the forecast period can be attributed to the emergence of gene therapies, precision medicine approaches, expanded access to therapies, long-term follow-up studies, and regulatory advancements. Major trends in the forecast period include the integration of digital health technologies, technological advancements in therapeutics, gene therapies, and genetic medicines, as well as regulatory support for orphan drugs and precision medicine approaches.
The growth of the Duchenne muscular dystrophy market is anticipated to be propelled by the increasing prevalence of chronic diseases. Chronic diseases are health conditions with enduring symptoms lasting for at least a year. Duchenne muscular dystrophy plays a role in the prevalence of chronic diseases as it addresses the specific therapeutic needs of individuals with this genetic disorder, underscoring the broader importance of personalized medicine in managing and potentially mitigating the impact of chronic conditions. For instance, as of January 2023, the National Institutes of Health (NIH), a U.S. government agency specializing in biomedical and health-related research, projects a significant increase in the prevalence of chronic diseases among the working-age population in the United States. The estimate indicates a 99.5% rise in adults aged 50 years and older with at least one chronic disease from 2020 to 2035. Moreover, the prevalence of multimorbidity is expected to surge by 110.5% from 2020 to 2050, highlighting the growing health challenges faced by the working population. Therefore, the increasing prevalence of chronic diseases is a key driver for the growth of the Duchenne muscular dystrophy market.
The growth of the Duchenne muscular dystrophy market is anticipated to be propelled by the increasing demand for personalized medicine. Personalized medicine involves tailoring medical treatment to an individual's unique characteristics, such as genetic makeup or lifestyle, leading to more effective and precise healthcare outcomes. In the context of Duchenne muscular dystrophy (DMD), the application of personalized medicine entails customizing treatments based on individual factors, enhancing therapeutic efficacy, and improving patient outcomes. For instance, as of December 2023, a report by The Personalized Medicine Coalition (PMC), a US-based nonprofit organization promoting the use of personalized medicine concepts, services, and products, reveals that personalized medicines constituted 35% of newly approved New Molecular Entities (NMEs) in 2021. They have consistently represented over a quarter of new therapeutics approved since 2015. Over the last six years, personalized medicines have consistently comprised more than a third of new drug approvals. Therefore, the growing demand for personalized medicine is a key driver for the Duchenne muscular dystrophy market's growth.
Technological advancements are a prominent trend gaining traction in the Duchenne muscular dystrophy market. Key companies within this market are intensifying their focus on technological advancements and investing in research and development to fortify their positions. For example, in April 2021, the Hamon Center for Regenerative Science and Medicine at the University of Texas Southwestern, a US-based public academic health science center, introduced an innovative gene therapy approach for treating mice with Duchenne muscular dystrophy (DMD). This approach utilizes CRISPR-Cas9-based techniques to restore a significant portion of the dystrophin protein, which is often deficient in many DMD patients. The researchers developed highly effective CRISPR-Cas9 nucleotide gene editing techniques to override the erroneous stop signal, leading to the restoration of 97% of the protein. This breakthrough involved the exploration of nucleotide gene editing techniques using cardiomyocytes derived from induced pluripotent stem cells (iPS cells) of DMD patients, demonstrating the successful restoration of the dystrophin protein.
Major players in the Duchenne muscular dystrophy market are directing their efforts towards product innovations, notably the development of the first gene therapy to treat Duchenne Muscular Dystrophy (DMD). This innovative therapy involves introducing functional copies of the dystrophin gene into affected individuals, aiming to correct the genetic mutation responsible for the progressive muscle degeneration associated with DMD. For instance, in June 2023, Sarepta Therapeutics, a US-based biopharmaceutical company specializing in RNA-based treatments for rare and infectious diseases, announced the FDA approval of ELEVIDYS, marking a significant milestone as the first gene therapy for Duchenne Muscular Dystrophy. This pioneering one-time treatment employs advanced gene therapy technology to target the root cause of the disease genetically. The approval of ELEVIDYS represents a paradigm shift in DMD treatment, moving beyond traditional supportive care approaches. It holds the potential to enhance patients' quality of life and life expectancy, showcasing the transformative impact of gene therapy on addressing rare diseases.
In December 2022, Solid Biosciences, a US-based life sciences company dedicated to advancing a portfolio of neuromuscular and cardiac programs, acquired AavantiBio for an undisclosed amount. This strategic acquisition positions the combined company to concentrate on the development of a diverse range of neuromuscular and cardiac programs, with a focus on advancing SGT-003, Solid's next-generation gene transfer candidate designed for the treatment of Duchenne muscular dystrophy. AavantiBio, Inc., a US-based biotechnology company, specializes in developing gene therapies aimed at transforming the lives of patients with rare genetic diseases.
Major companies operating in the duchenne muscular dystrophy market report are Pfizer Inc., GlaxoSmithKline plc, Eli Lilly and Company, Daiichi Sankyo Company Limited, PerkinElmer Inc., BioMarin Pharmaceutical Inc., Nippon Shinyaku Co. Ltd., Sarepta Therapeutics Inc., PTC Therapeutics Inc., Acceleron Pharma Inc., FibroGen Inc., Asklepios BioPharmaceutical Inc., Catabasis Pharmaceuticals Inc., Wave Life Sciences Ltd., Bristol Myers Squibb Company, BridgeBio Pharma Inc., CureVac N.V., Rocket Pharmaceuticals Inc., Italfarmaco SpA, Solid Biosciences Inc., Avidity Biosciences Inc., Fulcrum Therapeutics Inc., Akashi Therapeutics Inc., Nihon Pharmaceutical Co. Ltd., WAVE Life Sciences Ltd., Capricor Therapeutics Inc., Santhera Pharmaceuticals Holding, Armagen Technologies Inc., Dyne Therapeutics Inc., Benitec Biopharma Limited, Edgewise Therapeutics Inc.
North America was the largest region in the Duchenne muscular dystrophy market in 2023. Asia-Pacific is expected to be the fastest-growing region in the global duchenne muscular dystrophy market during the forecast period. The regions covered in the duchenne muscular dystrophy market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa. The countries covered in the duchenne muscular dystrophy market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain.
Duchenne Muscular Dystrophy therapies involve mutation suppression and the exon skipping approach. Exon skipping, a prevalent form of alternative splicing, removes introns and intervals on a pre-mRNA molecule, typically functioning as exons of a gene, when forming the final mRNA. Therapeutic classes include molecular-based therapies and steroid therapy, administered through oral, parenteral, and other routes. These therapies are distributed via hospital pharmacies, online pharmacies, and retail pharmacies, serving end-users such as hospitals, homecare, specialty clinics, and others.
The duchenne muscular dystrophy market research report is one of a series of new reports that provides Duchenne muscular dystrophy optical components market statistics, including Duchenne muscular dystrophy optical components industry global market size, regional shares, competitors with a Duchenne muscular dystrophy optical components market share, detailed Duchenne muscular dystrophy optical components market segments, market trends, and opportunities, and any further data you may need to thrive in the Duchenne muscular dystrophy optical components industry. This Duchenne muscular dystrophy optical components market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenario of the industry.
The duchenne muscular dystrophy market includes revenues earned by entities by providing respiratory therapy, physical therapy and gene therapy. The market value includes the value of related goods sold by the service provider or included within the service offering. Only goods and services traded between entities or sold to end consumers are included.
The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD, unless otherwise specified).
The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.
This product will be delivered within 3-5 business days.
The duchenne muscular dystrophy market size is expected to see strong growth in the next few years. It will grow to $1.61 billion in 2028 at a compound annual growth rate (CAGR) of 8.2%. The anticipated growth in the forecast period can be attributed to the emergence of gene therapies, precision medicine approaches, expanded access to therapies, long-term follow-up studies, and regulatory advancements. Major trends in the forecast period include the integration of digital health technologies, technological advancements in therapeutics, gene therapies, and genetic medicines, as well as regulatory support for orphan drugs and precision medicine approaches.
The growth of the Duchenne muscular dystrophy market is anticipated to be propelled by the increasing prevalence of chronic diseases. Chronic diseases are health conditions with enduring symptoms lasting for at least a year. Duchenne muscular dystrophy plays a role in the prevalence of chronic diseases as it addresses the specific therapeutic needs of individuals with this genetic disorder, underscoring the broader importance of personalized medicine in managing and potentially mitigating the impact of chronic conditions. For instance, as of January 2023, the National Institutes of Health (NIH), a U.S. government agency specializing in biomedical and health-related research, projects a significant increase in the prevalence of chronic diseases among the working-age population in the United States. The estimate indicates a 99.5% rise in adults aged 50 years and older with at least one chronic disease from 2020 to 2035. Moreover, the prevalence of multimorbidity is expected to surge by 110.5% from 2020 to 2050, highlighting the growing health challenges faced by the working population. Therefore, the increasing prevalence of chronic diseases is a key driver for the growth of the Duchenne muscular dystrophy market.
The growth of the Duchenne muscular dystrophy market is anticipated to be propelled by the increasing demand for personalized medicine. Personalized medicine involves tailoring medical treatment to an individual's unique characteristics, such as genetic makeup or lifestyle, leading to more effective and precise healthcare outcomes. In the context of Duchenne muscular dystrophy (DMD), the application of personalized medicine entails customizing treatments based on individual factors, enhancing therapeutic efficacy, and improving patient outcomes. For instance, as of December 2023, a report by The Personalized Medicine Coalition (PMC), a US-based nonprofit organization promoting the use of personalized medicine concepts, services, and products, reveals that personalized medicines constituted 35% of newly approved New Molecular Entities (NMEs) in 2021. They have consistently represented over a quarter of new therapeutics approved since 2015. Over the last six years, personalized medicines have consistently comprised more than a third of new drug approvals. Therefore, the growing demand for personalized medicine is a key driver for the Duchenne muscular dystrophy market's growth.
Technological advancements are a prominent trend gaining traction in the Duchenne muscular dystrophy market. Key companies within this market are intensifying their focus on technological advancements and investing in research and development to fortify their positions. For example, in April 2021, the Hamon Center for Regenerative Science and Medicine at the University of Texas Southwestern, a US-based public academic health science center, introduced an innovative gene therapy approach for treating mice with Duchenne muscular dystrophy (DMD). This approach utilizes CRISPR-Cas9-based techniques to restore a significant portion of the dystrophin protein, which is often deficient in many DMD patients. The researchers developed highly effective CRISPR-Cas9 nucleotide gene editing techniques to override the erroneous stop signal, leading to the restoration of 97% of the protein. This breakthrough involved the exploration of nucleotide gene editing techniques using cardiomyocytes derived from induced pluripotent stem cells (iPS cells) of DMD patients, demonstrating the successful restoration of the dystrophin protein.
Major players in the Duchenne muscular dystrophy market are directing their efforts towards product innovations, notably the development of the first gene therapy to treat Duchenne Muscular Dystrophy (DMD). This innovative therapy involves introducing functional copies of the dystrophin gene into affected individuals, aiming to correct the genetic mutation responsible for the progressive muscle degeneration associated with DMD. For instance, in June 2023, Sarepta Therapeutics, a US-based biopharmaceutical company specializing in RNA-based treatments for rare and infectious diseases, announced the FDA approval of ELEVIDYS, marking a significant milestone as the first gene therapy for Duchenne Muscular Dystrophy. This pioneering one-time treatment employs advanced gene therapy technology to target the root cause of the disease genetically. The approval of ELEVIDYS represents a paradigm shift in DMD treatment, moving beyond traditional supportive care approaches. It holds the potential to enhance patients' quality of life and life expectancy, showcasing the transformative impact of gene therapy on addressing rare diseases.
In December 2022, Solid Biosciences, a US-based life sciences company dedicated to advancing a portfolio of neuromuscular and cardiac programs, acquired AavantiBio for an undisclosed amount. This strategic acquisition positions the combined company to concentrate on the development of a diverse range of neuromuscular and cardiac programs, with a focus on advancing SGT-003, Solid's next-generation gene transfer candidate designed for the treatment of Duchenne muscular dystrophy. AavantiBio, Inc., a US-based biotechnology company, specializes in developing gene therapies aimed at transforming the lives of patients with rare genetic diseases.
Major companies operating in the duchenne muscular dystrophy market report are Pfizer Inc., GlaxoSmithKline plc, Eli Lilly and Company, Daiichi Sankyo Company Limited, PerkinElmer Inc., BioMarin Pharmaceutical Inc., Nippon Shinyaku Co. Ltd., Sarepta Therapeutics Inc., PTC Therapeutics Inc., Acceleron Pharma Inc., FibroGen Inc., Asklepios BioPharmaceutical Inc., Catabasis Pharmaceuticals Inc., Wave Life Sciences Ltd., Bristol Myers Squibb Company, BridgeBio Pharma Inc., CureVac N.V., Rocket Pharmaceuticals Inc., Italfarmaco SpA, Solid Biosciences Inc., Avidity Biosciences Inc., Fulcrum Therapeutics Inc., Akashi Therapeutics Inc., Nihon Pharmaceutical Co. Ltd., WAVE Life Sciences Ltd., Capricor Therapeutics Inc., Santhera Pharmaceuticals Holding, Armagen Technologies Inc., Dyne Therapeutics Inc., Benitec Biopharma Limited, Edgewise Therapeutics Inc.
North America was the largest region in the Duchenne muscular dystrophy market in 2023. Asia-Pacific is expected to be the fastest-growing region in the global duchenne muscular dystrophy market during the forecast period. The regions covered in the duchenne muscular dystrophy market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa. The countries covered in the duchenne muscular dystrophy market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Canada, Italy, Spain.
Duchenne Muscular Dystrophy therapies involve mutation suppression and the exon skipping approach. Exon skipping, a prevalent form of alternative splicing, removes introns and intervals on a pre-mRNA molecule, typically functioning as exons of a gene, when forming the final mRNA. Therapeutic classes include molecular-based therapies and steroid therapy, administered through oral, parenteral, and other routes. These therapies are distributed via hospital pharmacies, online pharmacies, and retail pharmacies, serving end-users such as hospitals, homecare, specialty clinics, and others.
The duchenne muscular dystrophy market research report is one of a series of new reports that provides Duchenne muscular dystrophy optical components market statistics, including Duchenne muscular dystrophy optical components industry global market size, regional shares, competitors with a Duchenne muscular dystrophy optical components market share, detailed Duchenne muscular dystrophy optical components market segments, market trends, and opportunities, and any further data you may need to thrive in the Duchenne muscular dystrophy optical components industry. This Duchenne muscular dystrophy optical components market research report delivers a complete perspective of everything you need, with an in-depth analysis of the current and future scenario of the industry.
The duchenne muscular dystrophy market includes revenues earned by entities by providing respiratory therapy, physical therapy and gene therapy. The market value includes the value of related goods sold by the service provider or included within the service offering. Only goods and services traded between entities or sold to end consumers are included.
The market value is defined as the revenues that enterprises gain from the sale of goods and/or services within the specified market and geography through sales, grants, or donations in terms of the currency (in USD, unless otherwise specified).
The revenues for a specified geography are consumption values that are revenues generated by organizations in the specified geography within the market, irrespective of where they are produced. It does not include revenues from resales along the supply chain, either further along the supply chain or as part of other products.
This product will be delivered within 3-5 business days.
Table of Contents
1. Executive Summary2. Duchenne Muscular Dystrophy Market Characteristics3. Duchenne Muscular Dystrophy Market Trends and Strategies32. Global Duchenne Muscular Dystrophy Market Competitive Benchmarking33. Global Duchenne Muscular Dystrophy Market Competitive Dashboard34. Key Mergers and Acquisitions in the Duchenne Muscular Dystrophy Market
4. Duchenne Muscular Dystrophy Market - Macro Economic Scenario
5. Global Duchenne Muscular Dystrophy Market Size and Growth
6. Duchenne Muscular Dystrophy Market Segmentation
7. Duchenne Muscular Dystrophy Market Regional and Country Analysis
8. Asia-Pacific Duchenne Muscular Dystrophy Market
9. China Duchenne Muscular Dystrophy Market
10. India Duchenne Muscular Dystrophy Market
11. Japan Duchenne Muscular Dystrophy Market
12. Australia Duchenne Muscular Dystrophy Market
13. Indonesia Duchenne Muscular Dystrophy Market
14. South Korea Duchenne Muscular Dystrophy Market
15. Western Europe Duchenne Muscular Dystrophy Market
16. UK Duchenne Muscular Dystrophy Market
17. Germany Duchenne Muscular Dystrophy Market
18. France Duchenne Muscular Dystrophy Market
19. Italy Duchenne Muscular Dystrophy Market
20. Spain Duchenne Muscular Dystrophy Market
21. Eastern Europe Duchenne Muscular Dystrophy Market
22. Russia Duchenne Muscular Dystrophy Market
23. North America Duchenne Muscular Dystrophy Market
24. USA Duchenne Muscular Dystrophy Market
25. Canada Duchenne Muscular Dystrophy Market
26. South America Duchenne Muscular Dystrophy Market
27. Brazil Duchenne Muscular Dystrophy Market
28. Middle East Duchenne Muscular Dystrophy Market
29. Africa Duchenne Muscular Dystrophy Market
30. Duchenne Muscular Dystrophy Market Competitive Landscape and Company Profiles
31. Duchenne Muscular Dystrophy Market Other Major and Innovative Companies
35. Duchenne Muscular Dystrophy Market Future Outlook and Potential Analysis
36. Appendix
Executive Summary
Duchenne Muscular Dystrophy Global Market Report 2024 provides strategists, marketers and senior management with the critical information they need to assess the market.This report focuses on duchenne muscular dystrophy market which is experiencing strong growth. The report gives a guide to the trends which will be shaping the market over the next ten years and beyond.
Reasons to Purchase
- Gain a truly global perspective with the most comprehensive report available on this market covering 50+ geographies.
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- Assess the Russia-Ukraine war’s impact on agriculture, energy and mineral commodity supply and its direct and indirect impact on the market.
- Measure the impact of high global inflation on market growth.
- Create regional and country strategies on the basis of local data and analysis.
- Identify growth segments for investment.
- Outperform competitors using forecast data and the drivers and trends shaping the market.
- Understand customers based on the latest market shares.
- Benchmark performance against key competitors.
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- Report will be updated with the latest data and delivered to you with an Excel data sheet for easy data extraction and analysis.
- All data from the report will also be delivered in an excel dashboard format.
Where is the largest and fastest growing market for duchenne muscular dystrophy? How does the market relate to the overall economy, demography and other similar markets? What forces will shape the market going forward? This report answers all these questions and many more.
The report covers market characteristics, size and growth, segmentation, regional and country breakdowns, competitive landscape, market shares, trends and strategies for this market. It traces the market’s historic and forecast market growth by geography.
- The market characteristics section of the report defines and explains the market.
- The market size section gives the market size ($b) covering both the historic growth of the market, and forecasting its development.
- The forecasts are made after considering the major factors currently impacting the market. These include:
- The impact of sanctions, supply chain disruptions, and altered demand for goods and services due to the Russian Ukraine war, impacting various macro-economic factors and parameters in the Eastern European region and its subsequent effect on global markets.
- The impact of higher inflation in many countries and the resulting spike in interest rates.
- The continued but declining impact of COVID-19 on supply chains and consumption patterns.
- Market segmentations break down the market into sub markets.
- The regional and country breakdowns section gives an analysis of the market in each geography and the size of the market by geography and compares their historic and forecast growth. It covers the growth trajectory of COVID-19 for all regions, key developed countries and major emerging markets.
- The competitive landscape chapter gives a description of the competitive nature of the market, market shares, and a description of the leading companies. Key financial deals which have shaped the market in recent years are identified.
- The trends and strategies section analyses the shape of the market as it emerges from the crisis and suggests how companies can grow as the market recovers.
Report Scope
Markets Covered:1) By Therapy: Mutation Suppression; Exon Skipping Approach
2) By Therapeutic Class: Molecular Based Therapies; Steroid Therapy
3) By Route of Administration: Oral; Parenteral; Other Routes Of Administration
4) By Distribution Channel: Hospital Pharmacy; Online Pharmacy; Retail Pharmacy
5) By End-user: Hospitals; Homecare; Specialty Clinics; Other End-Users
Key Companies Mentioned: Pfizer Inc.; GlaxoSmithKline plc; Eli Lilly and Company; Daiichi Sankyo Company Limited; PerkinElmer Inc.
Countries: Australia; Brazil; China; France; Germany; India; Indonesia; Japan; Russia; South Korea; UK; USA; Canada; Italy; Spain
Regions: Asia-Pacific; Western Europe; Eastern Europe; North America; South America; Middle East; Africa
Time Series: Five years historic and ten years forecast
Data: Ratios of market size and growth to related markets, GDP proportions, expenditure per capita
Data Segmentation: Country and regional historic and forecast data, market share of competitors, market segments
Sourcing and Referencing: Data and analysis throughout the report is sourced using end notes
Delivery Format: PDF, Word and Excel Data Dashboard
Companies Mentioned (Partial List)
A selection of companies mentioned in this report includes, but is not limited to:
- Pfizer Inc.
- GlaxoSmithKline plc
- Eli Lilly and Company
- Daiichi Sankyo Company Limited
- PerkinElmer Inc.
- BioMarin Pharmaceutical Inc.
- Nippon Shinyaku Co. Ltd.
- Sarepta Therapeutics Inc.
- PTC Therapeutics Inc.
- Acceleron Pharma Inc.
- FibroGen Inc.
- Asklepios BioPharmaceutical Inc.
- Catabasis Pharmaceuticals Inc.
- Wave Life Sciences Ltd.
- Bristol Myers Squibb Company
- BridgeBio Pharma Inc.
- CureVac N.V.
- Rocket Pharmaceuticals Inc.
- Italfarmaco SpA
- Solid Biosciences Inc.
- Avidity Biosciences Inc.
- Fulcrum Therapeutics Inc.
- Akashi Therapeutics Inc.
- Nihon Pharmaceutical Co. Ltd.
- WAVE Life Sciences Ltd.
- Capricor Therapeutics Inc.
- Santhera Pharmaceuticals Holding
- Armagen Technologies Inc.
- Dyne Therapeutics Inc.
- Benitec Biopharma Limited
- Edgewise Therapeutics Inc.
Methodology
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