Gene Synthesis (Research Use) - Global Stategic Business Report

The global market for Gene Synthesis (Research Use) was estimated at US$2.1 Billion in 2024 and is projected to reach US$4.5 Billion by 2030, growing at a CAGR of 14.0% from 2024 to 2030. This comprehensive report provides an in-depth analysis of market trends, drivers, and forecasts, helping you make informed business decisions. The report includes the most recent global tariff developments and how they impact the Gene Synthesis (Research Use) market.

Global Gene Synthesis (Research Use) Market - Key Trends & Drivers Summarized

Why Is Gene Synthesis Transforming Research in Genetic Engineering?

Gene synthesis has become an indispensable tool in modern molecular biology, enabling researchers to create custom DNA sequences with high precision and efficiency. Unlike traditional cloning techniques that rely on existing genetic material, gene synthesis allows scientists to design and construct novel genes from scratch, facilitating breakthroughs in synthetic biology, genetic engineering, and biomedical research. This capability has revolutionized studies in gene function, protein engineering, and drug discovery, making gene synthesis a critical resource for research institutions, pharmaceutical companies, and biotech firms.

Advancements in DNA assembly technologies, such as enzymatic synthesis and chip-based DNA printing, have significantly reduced synthesis costs while increasing speed and accuracy. Automated gene synthesis platforms now allow for the rapid generation of long and complex DNA sequences, enabling large-scale genomic studies and high-throughput screening. The increasing adoption of gene synthesis in CRISPR research, vaccine development, and metabolic pathway engineering has further accelerated its demand. As scientists continue to explore new frontiers in genomics and personalized medicine, gene synthesis is poised to play a crucial role in unlocking the full potential of synthetic biology.

Which Research Fields Are Driving the Demand for Gene Synthesis?

Gene synthesis is widely utilized across multiple scientific disciplines, each benefiting from its ability to precisely manipulate genetic sequences. In synthetic biology, researchers use gene synthesis to design and optimize biological systems, enabling the production of biofuels, specialty chemicals, and engineered microbes for industrial applications. The pharmaceutical industry relies on synthesized genes for antibody development, protein expression studies, and vaccine production, particularly in mRNA-based vaccine research.

Agricultural biotechnology is another major sector leveraging gene synthesis for crop improvement and pest resistance studies. Scientists are engineering plant genomes to enhance drought tolerance, nutrient content, and yield performance, providing sustainable solutions to global food security challenges. Additionally, gene synthesis plays a vital role in virology and epidemiology, where researchers construct viral genomes to study pathogen evolution and develop targeted antiviral therapies. The growing demand for precision genetics in these fields continues to fuel the expansion of the gene synthesis market, making it an essential tool for cutting-edge scientific research.

What Are the Latest Technological Advancements in Gene Synthesis?

Technological advancements in gene synthesis have significantly improved the accuracy, efficiency, and scalability of DNA synthesis processes. One of the most groundbreaking innovations is enzymatic DNA synthesis, which eliminates the need for traditional phosphoramidite chemistry, reducing chemical waste and increasing synthesis speed. This approach has enabled the development of cost-effective and environmentally friendly gene synthesis methods, making DNA fabrication more accessible to researchers worldwide.

Additionally, the integration of artificial intelligence (AI) and machine learning in gene design and optimization has enhanced sequence assembly, reducing error rates and improving functional gene expression. AI-driven algorithms can predict secondary structures, codon biases, and regulatory elements, ensuring optimal gene performance in experimental systems. The use of microfluidic platforms and high-throughput DNA synthesis techniques has also accelerated the production of large DNA libraries for applications such as protein engineering and directed evolution. These technological advancements are revolutionizing gene synthesis, enabling scientists to push the boundaries of genetic research with unprecedented precision.

What Factors Are Fueling the Growth of the Gene Synthesis Market?

The growth in the gene synthesis market is driven by several factors, including increasing demand for synthetic biology applications, advancements in DNA synthesis technology, and expanding research in genetic engineering. The pharmaceutical and biotechnology sectors are investing heavily in synthetic gene constructs for drug discovery, antibody engineering, and vaccine development, contributing to market expansion. Additionally, government funding for genomics research and synthetic biology initiatives has further propelled demand for gene synthesis services.

The growing need for customized genetic constructs in agricultural biotechnology, industrial microbiology, and metabolic engineering has also boosted market adoption. The rise of cloud-based bioinformatics platforms and AI-driven gene design tools has made gene synthesis more efficient and cost-effective, allowing researchers to accelerate discovery and innovation. Furthermore, the increasing use of gene synthesis in personalized medicine and gene therapy research is expected to drive long-term market growth. As the field of synthetic biology continues to evolve, gene synthesis will remain a fundamental technology shaping the future of genetic research and biotechnological advancements.

Report Scope

The report analyzes the Gene Synthesis (Research Use) market, presented in terms of market value (US$ Thousand). The analysis covers the key segments and geographic regions outlined below.

Segments: Method (Solid-Phase Synthesis, Chip-based Synthesis, PCR-based Enzyme Synthesis); Service (Antibody DNA Synthesis Service, Viral DNA Synthesis Service, Other Services); Research Phase (Pre-Clinical Research Phase, Clinical Research Phase); Application (Gene & Cell Therapy Development Application, Vaccine Development Application, Other Applications); End-Use (Biotechnology & Pharmaceutical Companies End-Use, Academic & Government Research Institutes End-Use, Contract Research Organizations End-Use)

Geographic Regions/Countries: World; United States; Canada; Japan; China; Europe (France; Germany; Italy; United Kingdom; Spain; Russia; and Rest of Europe); Asia-Pacific (Australia; India; South Korea; and Rest of Asia-Pacific); Latin America (Argentina; Brazil; Mexico; and Rest of Latin America); Middle East (Iran; Israel; Saudi Arabia; United Arab Emirates; and Rest of Middle East); and Africa.

Key Insights:

• Market Growth: Understand the significant growth trajectory of the Solid-Phase Synthesis segment, which is expected to reach US$2.4 Billion by 2030 with a CAGR of a 12.9%. The Chip-based Synthesis segment is also set to grow at 15.1% CAGR over the analysis period.
• Regional Analysis: Gain insights into the U.S. market, estimated at $559.3 Million in 2024, and China, forecasted to grow at an impressive 18.5% CAGR to reach $953.4 Million by 2030. Discover growth trends in other key regions, including Japan, Canada, Germany, and the Asia-Pacific.

Why You Should Buy This Report:

• Detailed Market Analysis: Access a thorough analysis of the Global Gene Synthesis (Research Use) Market, covering all major geographic regions and market segments.
• Competitive Insights: Get an overview of the competitive landscape, including the market presence of major players across different geographies.
• Future Trends and Drivers: Understand the key trends and drivers shaping the future of the Global Gene Synthesis (Research Use) Market.
• Actionable Insights: Benefit from actionable insights that can help you identify new revenue opportunities and make strategic business decisions.

Key Questions Answered:

• How is the Global Gene Synthesis (Research Use) Market expected to evolve by 2030?
• What are the main drivers and restraints affecting the market?
• Which market segments will grow the most over the forecast period?
• How will market shares for different regions and segments change by 2030?
• Who are the leading players in the market, and what are their prospects?

Report Features:

• Comprehensive Market Data: Independent analysis of annual sales and market forecasts in US$ Million from 2024 to 2030.
• In-Depth Regional Analysis: Detailed insights into key markets, including the U.S., China, Japan, Canada, Europe, Asia-Pacific, Latin America, Middle East, and Africa.
• Company Profiles: Coverage of players such as ATUM (formerly DNA2.0), BaseClear, Bio Basic Inc., BioCat GmbH, Biomatik and more.
• Complimentary Updates: Receive free report updates for one year to keep you informed of the latest market developments.

Select Competitors (Total 43 Featured):

• ATUM (formerly DNA2.0)
• BaseClear
• Bio Basic Inc.
• BioCat GmbH
• Biomatik
• Bioneer Corporation
• Boster Biological Technology
• DNA Script
• Eurofins Genomics
• GENEWIZ (Azenta Life Sciences)
• Geneworks Pty Ltd.
• GenScript
• Integrated DNA Technologies
• Macrogen
• OriGene Technologies
• ProteoGenix
• Sangon Biotech
• Synbio Technologies
• Thermo Fisher Scientific
• Twist Bioscience

Tariff Impact Analysis: Key Insights for 2025

Global tariff negotiations across 180+ countries are reshaping supply chains, costs, and competitiveness. This report reflects the latest developments as of April 2025 and incorporates forward-looking insights into the market outlook.

The analysts continuously track trade developments worldwide, drawing insights from leading global economists and over 200 industry and policy institutions, including think tanks, trade organizations, and national economic advisory bodies. This intelligence is integrated into forecasting models to provide timely, data-driven analysis of emerging risks and opportunities.

What’s Included in This Edition:

• Tariff-adjusted market forecasts by region and segment
• Analysis of cost and supply chain implications by sourcing and trade exposure
• Strategic insights into geographic shifts

Buyers receive a free July 2025 update with:

• Finalized tariff impacts and new trade agreement effects
• Updated projections reflecting global sourcing and cost shifts
• Expanded country-specific coverage across the industry