Results for tag: "Irinotecan"

Irinotecan is a semi-synthetic derivative of the natural product camptothecin, a quinoline alkaloid found in the bark of the Chinese tree Camptotheca acuminata. It is used as an antineoplastic agent in the treatment of a variety of cancers, including colorectal, lung, ovarian, and pancreatic cancer. Irinotecan is a topoisomerase I inhibitor, meaning it interferes with the enzyme topoisomerase I, which is involved in DNA replication. Irinotecan is available in both generic and branded forms, with the branded form being marketed under the trade name Camptosar. It is available in both intravenous and oral formulations, and is typically administered in combination with other chemotherapy agents. The Irinotecan market is highly competitive, with a number of major players operating in the space. These include Pfizer, Teva Pharmaceuticals, Mylan, Sandoz, and Sun Pharmaceuticals. Additionally, there are a number of smaller players operating in the market, such as Dr. Reddy's Laboratories, Intas Pharmaceuticals, and Natco Pharma. Show Less Read more